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Pfander, Boris

Dr. Boris Pfander

Otto-Hahn Research Group on DNA Replication & Genome Integrity, Max-Planck-Institute of Biochemistry


Project A23: Chromatin as limiting factor in the regulation of DNA repair pathway choice


Max-Planck Institute of Biochemistry
Am Klopferspitz 18
82152 Martinsried

Phone: +49 (0)89 85783050
Fax: +49 (0)89 85783022

Website: DNA Replication & Genome Integrity

Work group

Project A23

Curriculum Vitae

Academic Education

  • 2000 Diploma in Biochemistry, University of Hannover & Hannover Medical School, Germany. Thesis on “Characterization of NGF-induced phosphorylation of endocytotic proteins in PC12-cells“, Supervisor: Dr. Rudolf Bauerfeind

Advanced Professional Degrees

  • 2005 PhD in Biology, Ludwig-Maximilians University Munich, Germany & Max-Planck Institute of Biochemistry, Martinsried, Germany; Thesis: “Regulation of genome stability by SUMO- and ubiquitin-modification of PCNA“

Positions held

  • since 2010 Research Group leader (Otto-Hahn Research Group, W2) Max-Planck Institute of Biochemistry, Martinsried, Germany 
  • 2006- 2010 Postdoctoral work at London Research Institute, CRUK, South Mimms, UK, Chromosome Replication Lab (Prof. John Diffley) 
  • 2005- 2006 Postdoctoral work at the Max Planck Institute of Biochemistry, Martinsried, Germany, Dept. of Molecular Cell Biology (Prof. Stefan Jentsch) 
  • 2001-2005 PhD work at the Max Planck Institute of Biochemistry, Martinsried, Germany, Dept. of Molecular Cell Biology (Prof. Stefan Jentsch)

Honors and Awards

  • 2007- 2010 Human Frontier Science Program Long Term Fellowship 
  • 2007 EMBO Long Term Fellowship
  • 2006 - 2010 Cancer Research UK Research Fellowship
  • 2006 Otto-Hahn Award (Opportunity to start an independent Junior Research Group – Max-Planck Society, Germany) 
  • 2006 Otto-Hahn Medal (Max-Planck Society, Germany) 
  • 2006 MPIB Junior Research Award (Max-Planck Institute of Biochemistry, Martinsried, Germany)

Other professional activities

  • since 2016 Treasurer and elected Board Member, German Society of DNA Repair Research (DGDR)
  • 2016 Elected Representative of Research Group Leaders (Max Planck Institute of Biochemistry)
  • 2016 member of the organizing committee of the conference “DNA Repair”, Essen, Germany
  • 2014-2016 member of the Advisory Board, German Society of DNA Repair Research (DGDR)
  • since 2014 External member of PhD examination boards and thesis advisory committees at ETH Zürich, Switzerland; University of Ulm; LMU Munich
  • since 2011 Reviewer for >10 scientific journals
  • since 2011 Reviewer for funding agencies (German Research Council (DFG), Max Planck Society, Medical Research Council, UK, Swiss National Science Foundation, Wellcome Trust, UK)
  • since 2010 Junior Faculty Member - International Max Planck Research School (IMPRS) „From Biology to Medicine‟

Selected CRC project-releated publications

Bittmann J, Grigatis R, Amarell S, Galanti L, Wilfling F, Matos J, Pfander B*. (2020) A toolbox for cell cycle restricted protein expression in yeast reveals principles underlying regulation of structure-selective nucleases
eLife. doi: 10.7554/eLife.52459.

Lee C, Wilfling F, Ronchi P, Allegretti M, Mosalaganti S, Jentsch S, Beck M*, Pfander B*. (2020) Selective autophagy degrades nuclear pore complexes.
Nature Cell Biology. 22(2), 159-166, doi: 10.1038/s41556-019-0459-2

Bantele SC, Lisby M, Pfander B*. (2019). Quantitative sensing of ssDNA accumulation by DNA damage checkpoint mediators.
Nature Communications. 10, doi: 10.1038/s41467-019-08889-5

Lademann CA, Renkawitz J, Pfander B*, Jentsch S (2017). The INO80 complex removes H2A.Z to promote presynaptic filament formation during homologous recombination.
Cell Reports. 19(7):1294-1303

Bantele SC, Ferreira P, Gritenaite D, Boos D, Pfander B* (2017). Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection.
eLife. doi: 10.7554/eLife.21687.