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Eick, Dirk

Prof. Dr. Dirk Eick

Helmholtz-Zentrum München, Molecular Epigenetics

Responsibilities

Project A08: RNAPII_CTD interactions with chromatin – crosstalk between the codes

Contact

Phone: +49 (0)89 31871 - 512
Fax: +49 (0)89 7099 - 500

Website: Research Unit Molecular Epigenetics

Work group

Project A08

Curriculum Vitae

Academic Education

  • 1975 Biological Sciences, University of Cologne
  • 1980 Diploma in Genetics, University of Cologne

Advanced Professional Degrees

  • 1983 Ph.D., Genetics, University of Cologne
  • 1989 Habilitation, Virology, University of Freiburg

Positions held

  • 1983-1989 Postdoc/Senior Scientist, Institute of Virology, University of Freiburg
  • 1990-2008 Independent research group at the Institute of Clinical Molecular Biology and Tumour Genetics, Helmholtz Center Munich
  • since 1990 Member of the Faculty of Biology, Ludwig-Maximilians-University, Munich
  • since 2008 Head of the Department of Molecular Epigenetics, Helmholtz Center Munich

Honours and Awards

  • since 2009 Editorial Board, Transcription
  • since 2007 Member of the Excellence Cluster ‘Munich Center for Integrated Protein Science Munich" (CiPSM)
  • since 2006 Advisory Board of Ingenium Pharmaceuticals GmbH
  • 2008 Science Day Prize, Helmholtz Association
  • 1997-2000 Task Force der DFG - Friedhelm Herrmann

Selected CRC project-related publications

Schuller, R., Forne, I., Straub, T., Schreieck, A., Texier, Y., Shah, N., Decker, T.M., Cramer, P., Imhof, A., and Eick, D. (2016). Heptad-Specific Phosphorylation of RNA Polymerase II CTD. Molecular Cell 61, 305-314.

Hintermair, C., Heidemann, M., Koch, F., Descostes, N., Gut, M., Gut, I., Fenouil, R., Ferrier, P., Flatley, A., Kremmer, E., Chapman, R.D., Andrau, J.C., and Eick, D. (2012). Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation. The EMBO Journal 31, 2784-2797.

Mayer, A., Heidemann, M., Lidschreiber, M., Schreieck, A., Sun, M., Hintermair, C., Kremmer, E., Eick, D., and Cramer, P. (2012). CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 336, 1723-1725.

Sims, R.J., 3rd, Rojas, L.A., Beck, D., Bonasio, R., Schuller, R., Drury, W.J., 3rd, Eick, D., and Reinberg, D. (2011). The C-terminal domain of RNA polymerase II is modified by site-specific methylation.Science 332, 99-103.

Akhtar, M.S., Heidemann, M., Tietjen, J.R., Zhang, D.W., Chapman, R.D., Eick, D., and Ansari, A.Z. (2009). TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II. Molecular Cell 34, 387-393.