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Hammerschmidt, Wolfgang

Prof. Dr. Wolfgang Hammerschmidt

Helmholtz-Zentrum München, Haematologikum

Responsibilities

Project A13: Epstein-Barr virus DNA acquires cellular chromatin early in infection

Contact

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Haematologikum
Research Unit Gene Vectors
Marchioninistrasse 25
81377 München
Germany

Phone: +49 (0)89 3187 - 1506
Fax: +49 (0)89 3187 - 4225

Website: Research Unit Gene Vectors

Work group

Project A13

Curriculum Vitae

Academic Education

  • 1981 State exam in veterinary medicine
  • 1976-1981 Study of Veterinary Medicine, Freie Universität Berlin (FU Berlin)

Advanced Professional Degrees

  • 1990 Habilitation in ‚ Tumorvirologie’ at the Medical Veterinary Faculty of the FU Berlin. Advisor Hanns Ludwig, "Venia legendi" (teaching certificate) in Tumor Virology
  • 1987 Promotion ‚summa cum laude’, Freie Universität Berlin (FU Berlin) Advisor: Ernst Hellmann, Freie Universität Berlin (FU Berlin)

Positions Held

  • since 1998 Director of Department, Research Unit Gene Vectors, Helmholtz Center Munich, and Affiliated Professor at the Ludwig Maximilians-University Munich
  • 1990 - 1997 Research Group Leader, Institute for Clinical Molecular Biology and Tumor Genetics,Helmholtz Center Munich, and Affiliated Professor at the Ludwig Maximilians-University Munich
  • 1989 Visiting Assistant Professor, McArdle Laboratory for Cancer Research, Madison,Wisconsin, USA
  • 1987-1988 McArdle Laboratory for Cancer Research, Madison, Wisconsin, USA, Training Fellowship of the DFG, Advisor: Bill Sugden
  • 1984-1987 Postdoctoral Fellow, Freie Universität Berlin (FU Berlin), Institute for Virology, Advisor: Hanns Ludwig

Honours and Awards

  • 1983 Heinrich Lüssen Award, Freie Universität Berlin
  • 1996 Löffler-Frosch Award of the German Society of Virology
  • 1996 Dr.-Emil-Salzer Award of the Land Baden-Württemberg
  • 2002 Aronson Award of the City of Berlin

Selected CRC project-related publications

Albanese, M., Tagawa, T., Bouvet, M., Maliquim, L., Lutter, D., Hoser, J., Hastreiter, M., Hayes, M., Sugden, B., Martin, L., Moosmann, A., and Hammerschmidt, W. (2016). Epstein-Barr viral miRNAs reduce immune surveillance by virus-specific CD8+ T-cells. Proc Natl Acad Sci U S A in press.

Tagawa, T., Albanese, M., Bouvet, M., Moosmann, A., Mautner, J., Heissmeyer,.V., Zielinski, C., Lutter, D., Hoser, J., Hastreiter, M., Hayes, M., Sugden, B., and Hammerschmidt, W. (2016). Epstein-Barr viral miRNAs inhibit antiviral CD4+ T-cell responses targeting IL-12 and peptide processing. J. Exp. Med. in press.

Jochum, S., Ruiss, R., Moosmann, A., Hammerschmidt, W., and Zeidler.R. (2012). RNAs in Epstein-Barr virions control early steps of infection. Proc. Natl. Acad. Sci. U S A 109, E1396-404.

Kalla, M., Schmeinck, A., Bergbauer, M., Pich, D., and Hammerschmidt, W. (2010). AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci U S A 107, 850-855.

Mancao, C., and Hammerschmidt, W. (2007). Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood 110, 3715-3721.