Disordered protein regions partner up the cBAF remodeler for a chromatin dance
Molecular Cell Spotlight article from the Ladurner lab
02.11.2023
Maren Heimhalt and Andreas Ladurner (2023 Nov 2) Disordered protein regions partner up the cBAF remodeler for a chromatin dance. Molecular Cell. 83:21, pp 3763-3765. https://doi.org/10.1016/j.molcel.2023.10.002
Cited as abstract from the article:
Intrinsically disordered protein regions form condensates and mediate interactions with factors that regulate gene activity. Patil et al.1 decode how such regions within the chromatin remodeler cBAF choreograph self-condensation and non-self interactions with transcriptional regulators, potentially impacting disease.