Cell-to-Cell Heterogeneity in Chromatin Structure
Cell-to-cell variability in cell populations permits adaptation to different environmental challenges. How heterogeneity is controlled at the chromatin level is largely unknown. This mini-symposium brings together experts in chromatin research and single-cell methods to develop new approaches to deconvolute dynamics and heterogeneity in chromatin structure in various systems.
Date: Friday, September 21, 2018
Time: 14:00 - 18:00
Venue: Small Lecture Hall (N02.040), Biomedical Center (BMC), Munich
Organizers: Sigurd Braun and Nicolai Siegel
Bassem Al-Sady San Francisco, Richard Bartfai Nijmegen, Magda Bienko Stockholm, Maria Colomé-Tatché Munich, Jane Mellor Oxford, Robert Schneider Munich, Angela Taddei Paris
Open to the scientific community: undergrad students, doctoral candidates, postdocs and all scientists.
All are welcome!
download poster (pdf, 865 KB)
Program: (download pdf, 453 KB)
14:10 Jane Mellor, University Oxford
From smRNA FISH to a mathematical model for gene expression: How antisense transcription modulates chromatin structure to alter rates of transcription elongation and transcript stability
14:32 Robert Schneider, Helmholtz Zentrum Munich
Regulation of gene induction and repression in individual cells
14:54 Nicolai Siegel, Munich
What controls heterogeneity in antigen expression?
15:16 Magda Bienko, Karolinska Institute Stockholm
Illuminating genome organization through integrated microscopy and sequencing
15:38 Richard Bartfai, University Nijmegen
The dark side of the Plasmodium chromatin
16:00 Coffee Break
16:30 Maria Colomé-Tatché, Helmholtz Zentrum Munich
(Single Cell) computational epigenomics
16:52 Sigurd Braun, LMU Munich
Regulators of silent chromatin
17:14 Bassem Al-Sady, UCSF, San Francisco
Dynamic single cell measurements in fission yeast unmask instability in the heterochromatin spreading reaction
17:36 Angela Taddei, Curie Institute Paris
Nuclear Dynamics upon quiescence entry and return to growth
18:00 Reception with Brezn & Beer