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CRC 1064 Chromatin Dynamics - RESEARCH PROGRAM 2017-2021

A01 - Peter Becker

Domino nucleosome remodeling complexes and histone H2A.V dynamics in transcription and DNA repair

A02 - Ulrike Gaul

Chromatin regulation at promoters and enhancers, a molecular-mechanistic analysis

A03 - Andreas Ladurner

A poly-ADP-ribose switch releases the autoinhibition of the oncogenic remodeler Alc1/Chd1L

A04 - Philipp Korber

Reading DNA sequence for nucleosome positioning by remodelers and barriers

A06 - Karl-Peter Hopfner

Structure and Mechanism of the INO80 complex

A07 - Felix Müller-Planitz

Nucleosome spacing in a folded chromatin environment

A08 - Dirk Eick

RNA Pol II CTD interactions with chromatin - crosstalk between the codes

A11 - Gunnar Schotta

Characterization of Morc3, a novel factor in retrotransposon silencing

A12 - Ralph Rupp

Regulation of embryonic cell plasticity by stage-specific histone modification profiles

A13 - W. Hammerschmidt

Epstein-Barr virus DNA acquires cellular chromatin early in infection

A15 - Jürg Müller

The role of histone H2A monoubiquitylation and deubiquitylation in Drosophila

A16 - Axel Imhof

Quality control during chromatin assembly

A17 - Heinrich Leonhardt

Dynamic changes of DNA modifications and chromatin states

A19 - Michaela Smolle

Maintenance of chromatin organization by Isw1a during gene transcription

A20 - Robert Schneider

Understanding the role of histone short chain lysine acylations in the regulation of chromatin function

A21 - Henriette Uhlenhaut

Involvement of histone methyl transferases in the anti-inflammatory actions of the Glucocorticoid Receptor

A22 - Sebastian Bultmann

Functional interplay between DNA methylation and polycomb during preimplantation development

A23 - Boris Pfander

Chromatin as limiting factor in the regulation of DNA repair pathway choice

A24 - M-E. Torres-Padilla

Systematic screening for factors controlling heterochromatin formation in the mouse embryo and their role in modulating cellular plasticity

A25 - Sigurd Braun

Role of the nuclear membrane protein Lem2 in silencing and genome surveillance

A26 - Christoph Kurat

Mechanisms of Chromatin Replication

Assoc. project: Till Bartke

Readout of chromatin modification states by epigenetic effectors

Assoc. project: Nicolai Siegel

Understanding chromatin dynamics in antigenic variation

Assoc. Project: Irina Solovei

Mechanisms of euchromatin and heterochromatin positioning in the nucleus

Assoc. Project: Julian Stingele

DNA-protein crosslinks: endogenous origins and cellular responses

Assoc. Project: Stefan Stricker

Editing cell identities