Seminars, Events & News

All SFB Seminars are scheduled here – please have a look for the upcoming events.
Seminars are regularly scheduled on Thursdays at 11:00 more

Join us for our annual meeting to learn about exciting chromatin research in Munich! more

Researchers give testimonies about their research motivations and the scientific community at the LMU Life Science Campus in Großhadern/Martinsried.
See CRC 1064 project leaders Henriette Uhlenhaut, Felix Müller-Planitz and Sigurd Braun as well as associates Stefan Stricker, Julian Stingele and Nicolai Siegel. more

The meeting offered outstanding speakers and poster presentations for exchange and discussion on the dynamic organisation of chromatin structure and their function to support nuclear processes.

October 10-12, 2019, Biomedical Center Munich, Small Lecture Hall N02.040
Many thanks to all participants for their contributions in making this a successful and interesting meeting! more

November 9, 2018
In honor of Dirk Eick: A career dedicated to understanding gene expression more

• Pol II Symposium Photo Gallery

September 12-13, 2018 at the BMC more

February 22, 2018 more

• Developmental Programming 2018 Photo Impressions
• Final program: Developmental Programming and Reprogramming

The 4th Munich Chromatin Symposium on Chromatin Dynamics took place from March 10-12, 2016. more

• Developmental Programming and Reprogramming
• Distinct patterns of RNA polymerase II and transcriptional elongation characterize mammalian genome activation
• CRC Project Leaders Schneider and Torres Padilla elected to Academia Europeae
• Alessandro Angerilli (AG Rupp) – The Xenopus animal cap transcriptome: Building a mucociliary epithelium
• Integrative analysis of macrophage Ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classes
• Autumn Swan Song
• Baldi et al. – Genome-wide Rules of Nucleosome Phasing in Drosophila
• Sandro Baldi, Philipp Korber and Peter Becker: Review article on nucleosomal arrays and chromatin folding
• Dr. Susanne Bantele awarded Otto-Hahn Medal
• Bartke and Bultmann characterize the E3 ubiquitin ligase mechanism of UHRF1 and its role in DNA methylation
• Peter Becker new chair of EMBL Council
• Bioimaging Day 2021
• Biotech Career Opportunities in Munich
• XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair
• Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler
• Máté Borsos et al. from the Torres-Padilla lab reports on genome-lamina interactions in the early mouse embryo
• CRISPR-tools for physiology & cell state changes - potential of transcriptional engineering and epigenome editing
• Entering the post-epigenomic age: back to epigenetics.
• Regulation of heterochromatin establishment during early mammalian development
• The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery
• Nucleolar release of rDNA repeats for repair involves SUMO-mediated untehering by the Cdc48/p97 segregase
• Alumni Career Get-together
• Cell-to-Cell Heterogeneity in Chromatin Structure
• Schotta lab reports on epigenetic regulation of pioneer transcription factor Foxa2
• A CDK-regulated chromatin segregase promoting chromosome replication
• When should I eat: A circadian view on food intake and metabolic regulation
• Chromatin Day, July 27, 2017
• Chromatin Day, July 20, 2018
• Chromatin Day, July 25, 2019
• Chromatin Day, Oct 1, 2020
• Chromatin "Morning" 2021 with Digitalks
• Chromatin Day, July 21, 2022
• SAVE THE DATE! Chromatin Day, July 27, 2023
• In retrospect: Chromatin Dynamics Symposium
• Benchmarking atlas-level data integration in single-cell genomics
• Chromatin Dynamics will continue for 4 more years!
• DAAD Award 2017 to IRTG member
• IRTG-SFB 1064 member receives the DAAD Award
• Cell-free genomics reveal intrinsic, cooperative and competitive determinants of chromatin interactions
• Profile features in LMU Einsichten – Das Forschungsmagazin
• CRC 1064 Associates named EMBO Young Investigators 2020
• EpIC - EpiGene3Sys meets INC_Spain to ChromDesign the Genome
• Chromatin and Epigenetics: From Mechanisms to Execution
• Epigenetik: Ewächst aus einem erweiterten Blick innerhalb der Genetik eine neue Verantwortung?
• Munich Epigenetics Spotlight 2020
• Munich Epigenetics Spotlight 2021
• Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes
• Cell-to-Cell Heterogeneity in Trypanosomes
• Nuclear architecture in nocturnal animals – Review by Irina Solovei and colleagues
• Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection
• Zygotic genome activation by the totipotency pioneer factor Nr5a2
• Morc3 silences endogenous retroviruses by enabling Daxx mediated histone H3.3 incorporation.
• IRTG members selected for EUGLOH Doctoral Camp on innovation and global health
• Guthmann, Burton, Torres-Padilla: Expression and phase separation potential of heterochromatin proteins ...
• A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling
• Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
• Trailblazer Lecture with Edith Heard, Director General EMBL Heidelberg
• Probing cell identity hierarchies by fate titration and collision during direct reprogramming
• Now Hiring: PhD positions
• CRC 1064 Seasons Greetings to All!
• Karl-Peter Hopfner receives ERC Advanced Grant
• Ignatova et al. reports on the involvement of METTL5 in pluripotency and developmental programs
• Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Mathylation Landscapes
• MIT:FUTURA 2018 prize goes to Moritz Völker-Albert and the EpiQMax Team
• interact 2020
• interact 2023 – Science & Translation
• DNA Double Strand Break Repair and Its Control by Nucleosome Remodeling
• Genomic nucleosome organization reconstituted with pure proteins
• New building blocks: nucleosomes as part of DNA origamis
• Quantitative RNA imaging in single live cells reveals age-dependent asymmetric inheritance
• Hari R. Singh (Ladurner lab) et al: A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene
• Spatial organization of transcribed eukaryotic genes
• Nature Communications paper from the Bultmann and Leonhardt labs
• Tunable light and drug induced depletion of target proteins
• H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function
• See the video: Life Scientists on Campus
• LSGN PhD Student GET-TOGETHER
• The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila
• IRTG member Vanessa Luzak contributes to Soapbox Science 2022
• 1st LSGN MEME ART CONTEST
• Histone post-translational modifications — cause and consequence of genome function
• "More than just an emergency relief program"
• Jürg Müller on the genetic transmission of gene locks
• 3rd Munich Yeast Meeting 2021
• 4th Munich Yeast Meeting
• DNA replication fork speed underlies cell fate changes and promotes reprogramming
• A protein assembly mediates Xist localization and gene silencing
• Oberbeckmann et al. (Korber lab) – Absolute nucleosome occupancy map for the yeast genome
• Oktoberfest Lecture 2017: Karolin Luger
• Oktoberfest Lecture 2018: Dirk Schübeler
• Oktoberfest Lecture 2019: Tony Kouzarides
• Oktoberfest Lecture: Stirling Churchman
• IRTG 1064 Open Science Forum
• Organtransplantation und Xenotransplantation
• Paris-Munich Epigenetics Workshop & Symposium
• Strand-specific ChIP-seq at DNA breaks distinguishes ssDNA versus dsDNA binding and refutes single-stranded nucleosomes
• Film: Picture a Scientist
• A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis
• Regulation of Transcription: RNA Pol II and Myc
• HP1β carries an acidic linker domain and requires H3K9me3 for phase separation
• Probing protein ubiquitination in live cells
• CRC 1064 funding renewal 2017-2021
• DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease
• IRTG member Hannah Reinking among the 2021 Römer Prize recipients
• See the film! Responsible Research July 20, 2017
• Reponsible Research 2021
• IRTG 1064 retreat in San Servolo, Venice
• Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions
• "Proteomics highlight of the year" awarded to Maria Robles
• Two 2019 Science papers from the lab of Maria Robles
• Maria Robles receives SRBR Junior Faculty Research Award
• Rodriguez-Terrones et al: A distinct metabolic state arises during the emergence of 2-cell-like cells
• The fork protection complex recruits FACT to reorganize nucleosomes during replication
• Müller lab: Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC
• Altered expression response upon repeated gene repression in single yeast cells
• The Secrets of Chromatin, September 12-13, 2018
• Sequencing Spotlight in September
• Succinylation of H3K122 destabilizes nucleosomes and enhances transcription
• Nicolai Siegel awarded ERC Consolidator Grant
• Siegel lab: Epigenetics in Trypanosomes
• The biogenesis and function of nucleosome arrays
• IRTG member Janet Tait gets up on her soapbox!
• Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice
• Solovei & Joffe: Small chromosomal regions position themselves autonomously according to their chromatin class
• Associate Irina Solovei on compartmentalization of inverted and conventional nuclei
• Cancer Epigenetics - Principles, Applications and Single-Cell Resolution
• Four IRTG members selected for Spetses Summer School 2022
• Molecular basis of human ATM kinase inhibition
• Julian Stingele receives Vallee Scholar Award
• TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
• Targeted removal of epigenetic barriers during transcriptional reprogramming.
• DNA-methylation: master or slave of neural fate decisions?
• Sustainable World: Global Challenges for Life Scientists
• Sustainable World 2022
• Swan Song Re-launch with Nik Eggers and Manuel Guthmann
• It's Swan Song Season! April 18, May 9 and June 6
• 5th International Munich Chromatin Symposium 2019
• Dynamics of nuclear architecture during early embryonic development and lessons from liveimaging
• Epigenetics: from molecules to ecosystems
• Identifying Specific Protein Interactors of Nucleosomes Carrying Methylated Histones Using Quantitative Mass Spectrometry
• Comprehensive chromatin proteomics resolves functional phases of pluripotency and identifies changes in regulatory components
• Henriette Uhlenhaut receives ERC Consolidator Grant
• Enhancer RNA Expression in Response to Glucocorticoid Treatment in Murine Macrophages
• The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
• Solidarity for Scientists
• High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression
• Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm
• SPRTN patient variants cause global-genome DNA-protein crosslink repair defects
• DNA–Protein Crosslinks and Their Resolution
• Wie kommuniziert Wissenschaft?
• SFB 1064 contributes: From Chromatin to RNA - A Systems View on Molecular Mechanisms
• The 6th German Xenopus Meeting
• The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair
• MeCP2-induced heterochromatin organization is driven by oligomerization-based liquid–liquid phase separation and restricted by DNA methylation
• A ubiquitin switch controls autocatalytic inactivationof the DNA–protein crosslink repair protease SPRTN