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Symposium Programme – Paris-Munich Epigenetics, June 14-16, 2023

Paris-Munich Epigenetics Workshop & Symposium 2023
Wednesday June 14 – Friday June 16, 2023
Max Planck Institute of Biochemistry
Large Auditorium of the T-Building,
Am Klopferspitz 18, 82152 Planegg-Martinsried

download program (PDF, 24 KB)

download poster index (PDF, 51 KB)

download abstract booklet (PDF, 5 MB, password required)

Symposium Programme:

Wednesday, June 14

15:00 - 17:00 Registration open – arrival of speakers & general participants

17:00 - 17:15 Welcome and introduction for symposium by the Organizers

Session 1 – DNA Methylation I – Chair: Heinrich Leonhardt

17:15 - 17:45 THOMAS CARELL  (CuP, LMU Munich)
                     High and specific anti-leukemic activity with a carbocyclic 5-azacytosine-based DNMT inhibitor

17:45 - 18:15 MAXIM GREENBERG (Institut Jacques Monod, Paris)
                     Non-canonical functions of DNA methylation during epigenetic reprogramming in mammals

18:15 - 19:00 EMBO YIP guest lecturer - EDDA SCHULZ (MPI Molecular Genetics Berlin)
                     Signal decoding at the Xist locus

     Speakers' dinner (beer garden Waldheim)
     Free evening in Munich for students/post-docs and other participants

Thursday, June 15

Session 2 – DNA Methylation II – Chair: Pierre-Antoine Defossez

09:00 - 09:30   DÉBORAH BOURC'HIS (Institut Curie, Paris)
                    DNA methylation and methylation control during early cellular decisions

09:30 - 10:00 HEINRICH LEONHARDT (Human Genetics & BioImaging, LMU Munich)
                    Regulation of DNA modifications in mammals

10:00 - 10:15 Short talk - Annika Menke (CuP, LMU Munich)
                     Modelling TET Enzyme Reactivity with Synthetic Iron(IV)-oxido Complexes
                     and a Variety of Epigenetically Relevant Substrates

10:15 - 10:30 Short talk - Margherita Mori (Université Paris Cité)
                     Deciphering DNA methylation maintenance mechanisms in response to UV damage in mammalian cells

     Coffee break in Foyer

Session 3 - Quantitative Approaches – Chair: Kikuë Tachibana

11:00 - 11:30 MARIA COLOMÉ-TATCHÉ (Physiological Chemistry, LMU Munich)
                     Studying heterogeneity in cell populations with epigenomic measurements

11:30 - 12:00 TILL BARTKE (Helmholtz Munich)
                     Decoding chromatin states by proteomic profiling of modification-dependent nucleosome readers

12:00 - 12:15 Short talk - Erika Chacin (BMC, LMU Munich)
                     Establishment and function of chromatin organization at replication origins

12:15 - 12:30 Short talk - Julien Richard Albert (Institut Jacques Monod, Paris)
                     Epigenetic switcheroo: A genetic and computational approach to investigate the interplay between
                     DNA methylation and Polycomb in mouse development

12:30 - 13:00 10 Poster Flash Talks (2.5 min. each)Yixuan Fu (University of Zurich), Teresa Urli (Institut Jacques Monod, Paris), Xiaoying Chen (Université Paris Cité), Emmanuel García Sánchez (IGBMC, Illkirch, France), Franziska Greulich (TU Munich), Arohi Khurana (IFE, Helmholtz Munich), Marlet Morales-Franco (Helmholtz Munich), Sandra Nitsch (IFE, Helmholtz Munich), Bihter Özdemir-Aygenli (IFE, Helmholtz Munich), Anuroop V Venkatasubramani (BMC, LMU Munich)

     Lunch break (MPI Canteen) – "Meet the Speakers" for students/post-docs

14:00 – 16:00 – Poster session (including selection of poster prize)

     Coffee, drinks and light snacks available in Foyer

Session 4 – Chromatin Regulation – Chair: Sophie Polo

16:00 - 16:30 PIERRE-ANTOINE DEFOSSEZ (Université Paris Cité)
                     New functions of UHRF1 in DNA methylation

16:30 - 17:00 RAPHAËL MARGUERON (Institut Curie Paris)
                     Polycomb complex PRC2 regulation in the germline

17:00 - 17:15 Short talk - Marlies Oomen (IES, Helmholtz Munich)
                      The transcriptional repertoire of transposable elements during mammalian preimplantation development

17:15 - 17:30 Short talk - Emeline Roger (Institut Curie Paris)
                     Chromatin and TE control: yet another discovered pathway

     Coffee break in Foyer

18:00 - 18:30 CLAIRE ROUGEULLE (Université Paris Cité)
                      Control of X chromosome activity in early primate development

18:30 - 19:00 KIKUË TACHIBANA (MPI Biochemistry, Martinsried)
                     Orphan nuclear receptor Nr5a2 is the “spark of life” that awakens the zygotic genome

19:00 - 19:30 MARIA ELENA TORRES-PADILLA (IES, Helmholtz Munich)
                      Epigenetic mechanisms of cellular plasticity and reprogramming to totipotency

     Buffet Dinner, Mix & Mingle with drinks and music in the MPI Canteen / outside (if weather permits)

Friday, June 16

Session 5 – Chromatin Dynamics – Chair: Till Bartke

09:00 - 09:30 GENEVIÈVE ALMOUZNI (Institut Curie Paris)
                  Histones variants and friends, a state of play for shaping chromatin and cell fate

09:30 - 10:00 SOPHIE POLO (Université Paris Cité)
                   Mitotic chromatin marking governs asymmetric segregation of DNA damage

10:00 - 10:15 Short talk - Anupam Bhoi (TU Dresden)
                     Conformational Dynamics of the ISWI nucleosome remodelling enzyme

10:15 - 10:30 Short talk - Lena Paasche (Institute for Genetics, JLU Giessen)
                     Function of the H2A.Z-associated protein ZNF512B in differentiation and chromatin organization processes

     Coffee break

11:00 - 11:15 Short talk - Lexi Gao (MPI Biochemistry, Martinsried)
                     Transfer RNA pools in human cells are controlled by selective gene expression

11:15 - 11:30 Short talk - Vera Manelli (Helmholtz Munich)
                     Neurog2 and its cofactors as potential drivers of enhancer-promoter contacts during mouse cortical development

11:30 - 12:00 PETER BECKER (Molecular Biology, LMU Munich)
                     Analysis of transcription factor interactions with in vitro-assembled naïve embryonic chromatin

12:00 - 12:15 Poster/Short Talk prizes and concluding remarks


End of Symposium - departure of speakers & general participants