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Fully-funded PhD position in Chromatin Biology

Fully-funded PhD position in Chromatin Biology

The opportunity:

Chromatin modifications are highly cell type-specific and essential in regulating cell fate decisions. Several histone marks can coexist on the same nucleosome, resulting in an immense theoretical number of combinatorial possibilities. In this project, we want to investigate if more combinations exist on the same nucleosome with relevant biological functions. If so, do they occur in all cell types, or are there even lineage-specific combinations? What is their biological function, and how are they regulated?

In this full-time PhD position you will be responsible for:

  • Explore the combinations of several key histone modifications using mass spectrometry.
  • Employ a novel epigenomics strategy to map combinatorial histone marks across cell types and tissues.
  • Study the biological function of selected combinations using cutting-edge technologies in cultured cells.
  • Computational analysis and data integration.

Who you are:

  • You have completed or are about to complete a Master's degree in molecular biology, genetics, biochemistry, or a related field. More information on the eligibility criteria can be found here.
  • Excellent communication and interpersonal skills are among your strengths. Fluency in English is essential.
  • You enjoy working with project members from diverse scientific and cultural backgrounds and are willing to learn continuously.
  • Previous experience with genomics data generation and analysis is a plus but optional.

The offer:

  • A fully-funded position for four years with a possibility for extension.
  • A gross salary starting at €2,825 in the first year and increasing to €3,060 (salary conforms to TV-L E13, 65%). End-of-year bonus.
  • Embedding in a structured graduate program committed to supporting doctoral candidates in their research goals, in good scientific practice, and achieving optimal qualifications for future careers.
  • You will be part of a culturally diverse, inclusive, and highly motivated research team in a leading scientific environment that shares these values.
  • Funding to attend international meetings and workshops in Europe.

Are you curious in learning more about the position?

Requirements:

Then I look forward to receiving your full application, including:

  1. Curriculum Vitae (PDF file, max. 2 pages, written in English).
  2. Short description of any research project carried out during your studies (MSc thesis, etc.). State the rationale and goals of the research, and indicate your own contributions to the results (~300 words).
  3. Describe your general research interests (~200 words).
  4. What do you find interesting about our research? (~200 words).
  5. Transcript (record of study) and degree certificate for all completed degrees. If provided by the university, please also upload the supplementary information.
  6. Temporary/provisional transcripts for degree programs in which you are currently enrolled.
  7. Successful candidates need to be fluent in written and spoken English.
  8. Contact details from at least two referees (one referee should be a direct supervisor, working with you for at least 6 months).

Please send your full application as a single PDF document (max. 5 MB) to villasenorlab@gmail.com

Important dates:

The application call closes on July 15, 2024.

Interviews with pre-selected candidates will take place in August 2024.

The research project may start anytime between October and December 2024.

 See the full job description at https://www.villasenorlab.org/opportunities