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Program: Chromatin Dynamics Symposium 2024

DAY 1, Wednesday, OCTOBER 9thChromatin Dynamics kandinsky nucleosome AI 20240222_200x

16.30  Registration (Lecture Hall lobby)

17.00  Opening remarks, Welcome, Introduction (PETER BECKER)

17.10 – 18.30  The EMBO KEYNOTE LECTURE: ANJA GROTH, Copenhagen, DK
                      Epigenetic cell memory: how cells copy their epigenome

18:30 – 19.30  Welcome Get-together – refreshments for all (Lecture Hall Lobby)

19.30 – 22.00  Speakers' Dinner

DAY 2, Thursday, OCTOBER 10th

08.30 – 09.00  Registration

Session 1: GENE EXPRESSION & DEVELOPMENT (CHAIRS: DAPHNE CABIANCA & STEFAN STRICKER)

09.00 – 09.30  EILEEN FURLONG (Heidelberg, DE)
                       Going loopy studying enhancer-promoter communication

09.30 – 09.45  Valentina Baderna  (Heidelberg, DE)
                       A chromatin-integrated reporter assay to disentangle genetic from epigenetic contribution to enhancer activation              

09.45 – 10.00  Ana Janeva (Munich, DE)  
                      Taking the HAT off: Histone Acetylation as a Barrier to Cell Fate Reprogramming             

10:00 – 10:30  PETRA HAJKOVA (London, UK)
                       Epigenetic memory: erasure and long-term maintenance             

10.30 – 11.00  Break (Refreshments)

11.00 - 11.15  Fred van Leeuwen (Amsterdam, NL)
                      
Locus-specific chromatin-proteome decoding uncovers mechanisms of RNA pol III regulation

11.15 - 11.30  Julia Varga (Mainz, DE)
                      
BAF Complexes in Intestinal Homeostasis and Colorectal Cancer


Session 2: CHROMATIN COMPARTMENTS (CHAIR: PHILIPP KORBER)

11.30 – 12.00 KARSTEN RIPPE (Heidelberg, DE) 
                      Bridging loops and hubs: The AC/DC model of gene regulation                

12.00 – 12.15  Felix Jonas (Bremen, DE)
                      Deciphering the molecular grammar of genome-specificity of yeast TF IDRs                

12.15 – 12.45  JOP KIND (Utrecht, NL)
                       Measuring single-cell chromatin transitions in time                 

12.45 – 13.30  Lunch Buffet (Lecture Hall Lobby)

13:30 - 15:30  Poster Session I (even numbers) (Poster Directory, pdf, 46 KB)


Session 3: CHROMATIN ARCHITECTURE (CHAIR: NICOLAI SIEGEL) 

15.30 – 16.00  EMBO YIP LECTURE MARIEKE OUDELAAR (Göttingen, DE) 
                      Mechanisms that drive 3D genome folding and their function in gene regulation                  

16.00 – 16.15  Simon Holzinger (Regensburg, DE)
                      Chromatin Architecture and Dynamics in Plasmodium falciparum: New Insights with the novel nucDetective Pipeline                  

16.15 – 16.30  Nils Krietenstein (Copenhagen, DK)
                      
FAcilitating Chromatin Transcription and Replication Controls Local and Global Chromatin Structure

16.30 - 16.45  Gabriela Stumberger (Munich, DE)
                       Nanoscopy of multiway promoter-enhancer topologies

16.45 - 17.00  Mrinmoy Pal (Munich, DE)
                      Low-input genomics screening reveals multiple epigenetic pathways that orchestrate nuclear organization in early mouse embryos

17.00 - 19.00  Poster Session II (odd numbers) and HAPPY HOUR. (Poster Directory, pdf, 46 KB)

19:00 – 22.00  DINNER, after-dinner drinks for everyone

DAY 3, Friday, OCTOBER 11th

Session 4: DNA REPLICATION & REPAIR  (CHAIR: TILL BARTKE)

09.00 – 09.30  EMBO YIP LECTURE FRANCESCA MATTIROLI (Utrecht, NL)
                      Acute multi-level response to defective de novo chromatin assembly in S-phase              

09.30 – 09.45  Stamatis Papathanasiou (Mainz, DE)
                      
Mitotic errors as a novel source of heritable (epi)genetic instability

09.45 – 10.00  Marcel Werner (Munich, DE)
                     
Transcription-Replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for  transcription recovery

10.00 – 10.30  EVI SOUTOGLOU (Brighton, UK)
                      Genome organization in DNA repair pathway choice and mutagenesis

10.30 – 11.00  Break (Refreshments)


Session 5: QUANTITATIVE & STRUCTURAL CHROMATIN BIOLOGY (CHAIR: RODRIGO VILLASEÑOR)

11.00 – 11.15  Announcement Poster Prize 

11.15 – 11.45  BEAT FIERZ (Lausanne, CH)
                      Decoding molecular mechanisms of chromatin PTM writing and erasing

11.45 - 12.00  Maik Engeholm (Göttingen, DE)
                      
Resolution of Transcription-Induced Hexasome-Nucleosome Complexes by Chd1 and FACT

12.00 – 12.15  Marcus Wilson (Edinburgh, UK)
                      
DNA methylation reading in nucleosomes requires novel MeCP2 DNA interactions

12.15 - 12.30  Marisa Müller (Munich, DE)
                     
Molecular basis for specific H4K16 acetylation by the Drosophila MOF/MSL complex

12.30 – 13.00  NICOLAS THOMÄ  (Lausanne, CH)
                      Nucleosomes gate cofactor access to the transcription factor p53              

13.00  Closing Remarks / End of meeting