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Arulanandam, Jeyaprakash

Prof. Arockia Jeyaprakash (JP) Arulanandam, Ph.D

Molecular mechanisms ensuring accurate centromere inheritance and error-free chromosome segregation

Responsibilities


Gene Center and LMU Department of Biochemistry

Associated Member since 2024

Contact

Gene Center and Department of Biochemistry
Ludwig-Maximilians-Universität München

Feodor-Lynen-Straße 25
81377 Munich
Germany


Website: Gene Center LMU, Structural Biology of Cell Division
Website: University of Edinburgh, Structural Biology of Cell Division

Curriculum Vitae

Academic Education

2005  PhD, Molecular Biophysics Unit, Indian Institute of Science, Inda
1998  MSc in Physics, The American College, Madurai, India

Current Positions

since Mar 2023  Professor & Group Leader, The Gene Centre, LMU Munich, Germany
since Aug 2022  Professor (Personal Chair) of Structural Cell Biology, Institute of Cell Biology, University of Edinburgh, UK
since Aug 2022  Co-Head, Institute of Cell Biology, University of Edinburgh, UK

Previous Positions

  • 2017 - 2022  Wellcome Career Development Fellow, Wellcome Centre for Cell Biology, University of Edinburgh, UK
  • 2012 - 2016  Wellcome Career Development Fellow, Wellcome Centre for Cell Biology, University of Edinburgh, UK
  • 2007 - 2011  Postdoctoral Researcher, Department of Structural Cell Biology, Max Planck Institute for Biochemistry, Martinsried, Germany
  • 2007 - 2011  Marie Curie Incoming International Fellow, EMBL-Heidelberg, Germany
  • 2004 - 2005  Alexander von Humboldt Fellow, EMBL-Heidelberg, Germany

Fellowships and Awards

  • 2017 - 2022  Wellcome Senior Research Fellowship
  • 2012 - 2016  Wellcome Carrier Development Fellowship
  • 2008             Max Planck Institute of Biochemistry Junior Research Award
  • 2005 - 2007  Marie Curie Incoming International Fellowship (European Commission)
  • 2004 - 2005  Alexander von Humboldt Fellowship
  • 2004            EMBO World Programme Fellowhip (declined)
  • 2002            IUPAP Travel Fellow
  • 1998            Einstein Award (for proficiency in Physics)

Major Grants

  • 2022 - 2027  ERC Advanced Grant 2021
  • 2022- 2025   Medical Research Council, UKRI
  • 2017 - 2022  Wellcome Senior Research Fellowship
  • 2015 - 2016  Wellcome Enhancement grant
  • 2013 - 2017  Marie-Curie Career Integration Grant (EC)
  • 2012 - 2016  Wellcome Carrier Development Fellowship

Selected Publications

Abad, M. A*., Gupta, T*., Hadders, M, A., Meppelink, A., Wopken, J. P., Blackburn, E., Zou, J., Gireesh, A., Buzuk, L., Kelly, D, A., McHugh, T., Rappsilber, J., Lens, S. M. A and Jeyaprakash, A. A§. Mechanistic Basis for Sgo1-Mediated Centromere Localisation and Function of the CPC. J. Cell Biol (2022) 221(8):e202108156 Doi: https://doi.org/10.1083/jcb.202108156

Medina-Pritchard, B., Lazou, V., Zou, J., Byron O., Abad, M. A., Rappsilber, J., Heun, P and Jeyaprakash, A. A§. Structural Basis for Centromere Maintenance by Drosophila CENP-A Chaperone Cal1. EMBO J (2020) Doi: https://doi.org/10.15252/embj.2019103234

Abad, M. A., Ruppert, J. G., Buzuk, L., Wear, M. A., Zou, J., Webb, K. M., Kelly, D. A., Voigt, P., Rappsilber, J., Earnshaw, W. C and Jeyaprakash, A. A§. Direct Nucleosome Binding of Borealin Secures Chromosome Association and Function of the CPC. J Cell Biol (2019) 218(12):3912-3925.

Spiller, F*., Medina-Pritchard, M*., Abad, M. A*., Wear, M. A., Molina, O., Earnshaw, W. C and Jeyaprakash, A. A§. Molecular Basis for Cdk1 Regulated Timing of Mis18 Complex Assembly and CENP-A Deposition. EMBO Rep (2017) 18:894-905. Doi:10.15252/embr.201643564.

Abad, M. A., Medina, B., Santamaria, A., Zou, J., Plasberg-Hill, C., Madhumalar, A., Jayachandran, U., Redli, P. M., Rappsilber, J., Nigg, E. A. and Jeyaprakash. A. A§. Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex. Nat Commun (2014) Jan13; 5:2964. Doi:10.1038/ncomms3964.