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Solovei, Irina

Dr. Irina Solovei

Mechanisms of euchromatin and heterochromatin positioning in the nucleus

Responsibilities



Biozentrum der LMU, Martinsried, Germany

Associated member since 2015

Contact

Human Biology and Bioimaging
Biozentrum, Department Biology II
Grosshadernerstr. 2
82152 Martinsried
Germany

Phone: + 49 (0)89 2180-74223

Website: http://www.bioimaging.bio.lmu.de/research/research-group_solovei/index.html

Curriculum Vitae

Academic Education

1981 Diploma in Biology; St.Petersburg University, Russia

Advanced Professional Degrees

1984 PhD; Advisors Dr. O. Chaga and Prof. A. A. Zavarzin, Deapartment of Cytology and Histology, St.Petersburg University, Russia

Positions held

  • since 2009 Principle Investigator in Ludwig Maximilians University of Munich, Biozentrum, Human Biology and BioImaging group
  • 1996-2009 Senior Research Scientist in Ludwig Maximilians University of Munich, laboratory of Prof. T. Cremer
  • 1985-1996 Postdoctoral associate with Prof. E. Gaginskaya, Biological Institute of St.Petersburg University, Russia Honours and Awards
  • 1990-1996 Several Wellcome Trust awards for work in Leicester University in the laboratory of Prof.H.Macgregor

Editorial activities

since 2009 Associated Editor of Chromosome Researcha Selected

Selected CRC project-related publications

Feodorova, Y., Falk, M., Mirny, L.A., and Solovei, I.* (2020). Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals. Trends Cell Biol 30, 276-289.

Falk, M., Feodorova, Y., Naumova, N., Imakaev, M., Lajoie, B.R., Leonhardt, H., Joffe, B., Dekker, J., Fudenberg, G.*, Solovei, I.*, Mirny, L.A.* (2019). Heterochromatin drives compartmentalization of inverted and conventional nuclei. Nature 570, 395-399.

van de Werken, H.J.G., Haan, J.C., Feodorova, Y., Bijos, D., Weuts, A., Theunis, K., Holwerda, S.J.B., Meuleman, W., Pagie, L., Thanisch, K., Kumar, P., Leonhardt, H., Marynen, P., van Steesel, B., Voet, T., de Laat, W., Solovei, I.* and Joffe, B. (2017). Small chromosomal regions position themselves autonomously according to their chromatin class. Genome Res 27, 922-933

Solovei I, Wang AS, Thanisch K, Schmidt CS, Krebs S, Zwerger M, Cohen TV, Devys D, Foisner R, Peichl L, Herrmann H, Blum H, Engelkamp D, Stewart CL, Leonhardt H and Joffe B (2013). LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation. Cell, 152, 584-59

Solovei I, Kreysing M, Lanctot C, Koesem S, Peichl L, Cremer T, Guck J and Joffe B (2009). Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution. Cell, 137, 356-368