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Hammerschmidt, Wolfgang

Prof. Dr. Wolfgang Hammerschmidt

Helmholtz-Zentrum München, Haematologikum


Project A13: Epstein-Barr virus DNA acquires cellular chromatin early in infection


Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Research Unit Gene Vectors
Marchioninistrasse 25
81377 München

Phone: +49 (0)89 3187 - 1506
Fax: +49 (0)89 3187 - 4225

Website: Helmholtz Zentrum Research Group EBV Genetics and Vectors

Work group

Project A13

Curriculum Vitae

Academic Education

  • 1981 State exam in veterinary medicine
  • 1976-1981 Study of Veterinary Medicine, Freie Universität Berlin (FU Berlin)

Advanced Professional Degrees

  • 1990 Habilitation in ‚ Tumorvirologie’ at the Medical Veterinary Faculty of the FU Berlin. Advisor Hanns Ludwig, "Venia legendi" (teaching certificate) in Tumor Virology
  • 1987 Promotion ‚summa cum laude’, Freie Universität Berlin (FU Berlin) Advisor: Ernst Hellmann, Freie Universität Berlin (FU Berlin)

Positions Held

  • since 1998 Director of Department, Research Unit Gene Vectors, Helmholtz Center Munich, and Affiliated Professor at the Ludwig Maximilians-University Munich
  • 1990 - 1997 Research Group Leader, Institute for Clinical Molecular Biology and Tumor Genetics,Helmholtz Center Munich, and Affiliated Professor at the Ludwig Maximilians-University Munich
  • 1989 Visiting Assistant Professor, McArdle Laboratory for Cancer Research, Madison,Wisconsin, USA
  • 1987-1988 McArdle Laboratory for Cancer Research, Madison, Wisconsin, USA, Training Fellowship of the DFG, Advisor: Bill Sugden
  • 1984-1987 Postdoctoral Fellow, Freie Universität Berlin (FU Berlin), Institute for Virology, Advisor: Hanns Ludwig

Honours and Awards

  • 1983 Heinrich Lüssen Award, Freie Universität Berlin
  • 1996 Löffler-Frosch Award of the German Society of Virology
  • 1996 Dr.-Emil-Salzer Award of the Land Baden-Württemberg
  • 2002 Aronson Award of the City of Berlin

Selected CRC project-related publications

Liu WH, Mrozek-Gorska P, Wirth AK, Herold T, Schwarzkopf L, Pich D, Völse K, Melo-Narváez MC, Carlet M, Hammerschmidt W, and Jeremias I. 2020. Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL. Biomark Res. 8:46.https://doi.org/10.1186/s40364-020-00226-z.

Buschle A, and Hammerschmidt W. 2020. Epigenetic lifestyle of Epstein-Barr virus. Semin Immunopathol. 42:131-142. https://doi.org/10.1007/s00281-020-00792-2. (Review article)

Pich D, Mrozek-Gorska P, Bouvet M, Sugimoto A, Akidil E, Grundhoff A, Hamperl S, Ling PD, and Hammerschmidt W. 2019. First days in the life of naive human B lymphocytes infected with Epstein-Barr virus. MBio. https://doi.org/10.1128/mBio.01723-19.

Mrozek-Gorska P, Buschle A, Pich D, Schwarzmayr T, Fechtner R, Scialdone A, and Hammerschmidt W. 2019. Epstein-Barr virus reprograms human B lymphocytes immediately in theprelatent phase of infection. Proc Natl Acad Sci U S A. 116:16046-16055. https://doi.org/10.1073/pnas.1901314116

Schaeffner M, Mrozek-Gorska P, Buschle A, Woellmer A, Tagawa T, Cernilogar FM, Schotta G, Krietenstein N, Lieleg C, Korber P, and Hammerschmidt W. 2019. BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV. Life Sci Alliance. https://doi.org/10.26508/lsa.201800108.