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Pfander, Boris

Prof. Dr. Boris Pfander

Professor for Genome Maintenance Mechanisms in Health and Disease, DLR Cologne

Responsibilities

Project A23: Chromatin as limiting factor in the regulation of DNA repair pathway choice

Contact

since October 2021

German Aerospace Center (DLR)
Institute of Aerospace Medicine
Genome Maintenance Mechanisms in Health and Disease
Radiation Biology
Linder Höhe
51147 Cologne
Germany
Phone: +49 2203 601 1277

and

Institute for Genome Stability in Ageing and Disease
Cologne University
CECAD Research Center
Joseph-Stelzmann-Str. 26
50931 Cologne
Germany

Phone: +49 2203 601 1277

Website: Genome Maintenance Mechanisms in Health and Disease

Work group

Project A23

Curriculum Vitae

Academic Education

  • 2000 Diploma in Biochemistry, University of Hannover & Hannover Medical School, Germany. Thesis on “Characterization of NGF-induced phosphorylation of endocytotic proteins in PC12-cells“, Supervisor: Dr. Rudolf Bauerfeind

Advanced Professional Degrees

  • 2005 PhD in Biology, Ludwig-Maximilians University Munich, Germany & Max-Planck Institute of Biochemistry, Martinsried, Germany; Thesis: “Regulation of genome stability by SUMO- and ubiquitin-modification of PCNA“

Positions held

  • since 2010 Research Group leader (Otto-Hahn Research Group, W2) Max-Planck Institute of Biochemistry, Martinsried, Germany 
  • 2006- 2010 Postdoctoral work at London Research Institute, CRUK, South Mimms, UK, Chromosome Replication Lab (Prof. John Diffley) 
  • 2005- 2006 Postdoctoral work at the Max Planck Institute of Biochemistry, Martinsried, Germany, Dept. of Molecular Cell Biology (Prof. Stefan Jentsch) 
  • 2001-2005 PhD work at the Max Planck Institute of Biochemistry, Martinsried, Germany, Dept. of Molecular Cell Biology (Prof. Stefan Jentsch)

Honors and Awards

  • 2007- 2010 Human Frontier Science Program Long Term Fellowship 
  • 2007 EMBO Long Term Fellowship
  • 2006 - 2010 Cancer Research UK Research Fellowship
  • 2006 Otto-Hahn Award (Opportunity to start an independent Junior Research Group – Max-Planck Society, Germany) 
  • 2006 Otto-Hahn Medal (Max-Planck Society, Germany) 
  • 2006 MPIB Junior Research Award (Max-Planck Institute of Biochemistry, Martinsried, Germany)

Other professional activities

  • since 2016 Treasurer and elected Board Member, German Society of DNA Repair Research (DGDR)
  • 2016 Elected Representative of Research Group Leaders (Max Planck Institute of Biochemistry)
  • 2016 member of the organizing committee of the conference “DNA Repair”, Essen, Germany
  • 2014-2016 member of the Advisory Board, German Society of DNA Repair Research (DGDR)
  • since 2014 External member of PhD examination boards and thesis advisory committees at ETH Zürich, Switzerland; University of Ulm; LMU Munich
  • since 2011 Reviewer for >10 scientific journals
  • since 2011 Reviewer for funding agencies (German Research Council (DFG), Max Planck Society, Medical Research Council, UK, Swiss National Science Foundation, Wellcome Trust, UK)
  • since 2010 Junior Faculty Member - International Max Planck Research School (IMPRS) „From Biology to Medicine‟


Selected CRC project-releated publications

Bittmann J, Grigatis R, Amarell S, Galanti L, Wilfling F, Matos J, Pfander B*. (2020) A toolbox for cell cycle restricted protein expression in yeast reveals principles underlying regulation of structure-selective nucleases
eLife. doi: 10.7554/eLife.52459.

Lee C, Wilfling F, Ronchi P, Allegretti M, Mosalaganti S, Jentsch S, Beck M*, Pfander B*. (2020) Selective autophagy degrades nuclear pore complexes.
Nature Cell Biology. 22(2), 159-166, doi: 10.1038/s41556-019-0459-2

Bantele SC, Lisby M, Pfander B*. (2019). Quantitative sensing of ssDNA accumulation by DNA damage checkpoint mediators.
Nature Communications. 10, doi: 10.1038/s41467-019-08889-5

Lademann CA, Renkawitz J, Pfander B*, Jentsch S (2017). The INO80 complex removes H2A.Z to promote presynaptic filament formation during homologous recombination.
Cell Reports. 19(7):1294-1303

Bantele SC, Ferreira P, Gritenaite D, Boos D, Pfander B* (2017). Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection.
eLife. doi: 10.7554/eLife.21687.