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Müller, Jürg

Dr. Jürg Müller

Max-Planck-Institute of Biochemistry, Martinsried


Project A15: The role of histone H2A monoubiquitylation and deubiquitylation in Drosophila


MPI of Biochemistry
Am Klopferspitz 18
82152 Martinsried

Phone: +49 (0)89 8578 - 3480

Website: Chromatin Biology

Work group

Project A15

Curriculum Vitae

Academic Education

  • 1983–1988 Studies in Zoology and Molecular Biology (Diploma), University of Zürich, Supervisor: Prof. Dr. Mariann Bienz

Advanced Professional Degrees

  • 1991 PhD in Zoology, University of Zürich, Supervisor: Prof. Dr. Mariann Bienz

Positions held

  • since July 2010 Group leader at the Max-Planck-Institute of Biochemistry in Martinsried, Germany
  • 2001-2010 Group leader in the Genome Biology Unit at the EMBL in Heidelberg, Germany
  • 1996-2001 Junior group leader at the Max-Planck-Institute for Developmental Biology in Tübingen, Germany
  • 1992-1996 Postdoctoral research at the MRC Laboratory of Molecular Biology in Cambridge, England (laboratory of Dr. P.A. Lawrence)


  • 2011 Elected Member of EMBO (European Molecular Biology Organisation)

Selected CRC project-related publications

Bonnet, J., Lindeboom, R.G.H., Pokrovsky, D., Stricker, G., Çelik, M.H., Rupp, R.A.W., Gagneur, J., Vermeulen, M., Imhof, A. and Müller, J. (2019). Quantification of proteins and histone marks in Drosophila embryos reveals stoichiometric relationships impacting chromatin regulation. Dev Cell, 51, 632-644.

Copur, O. and Müller, J. (2018). Histone demethylase activity of Utx is essential for viability and regulation of HOX gene expression in Drosophila. Genetics 208, 633-637.

Schmähling, S., Meiler, A., Lee, Y., Mohammed, A., Finkl, K., Tauscher, K., Israel, L., Borath, M., Philippou-Massier, J., Blum, H., Habermann, B., Imhof, A., Song, J.J. and Müller, J. (2018). Regulation and function of H3K36 di-methylation by the trithorax-group protein complex AMC. Development 145, doi: 10.1242/dev.163808

Copur, O., Gorchakov, A., Finkl, K., Kuroda, M.I. and Müller, J. (2018). Sex-specific phenotypes of histone H4 point mutants establish dosage compensation as the critical function of H4K16 acetylation in Drosophila. Proc. Natl. Acad. Sci. 115, 13336-13341.

Laprell, F., Finkl, K. and Müller, J. (2017). Propagation of Polycomb-repressed chromatin requires sequence-specific recruitment to DNA. Science 356, 85-88.