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Schotta, Gunnar

Prof. Dr. Gunnar Schotta

Biomedical Center - Molecular Biology, LMU Munich


Project A11: Characterization of Morc3, a novel factor in retrotransposon silencing


Biomedical Center
Molecular Biology
Großhaderner Str. 9
82152 Plangegg-Martinsried

Phone: +49 (0)89 2180 - 75422

Website: Epigenetic Gene Regulation

Work group

Project A11

Curriculum Vitae

Academic Education

  • 1997 Diploma thesis in biochemistry, Advisor: Dr. Rainer Dorn, Martin-Luther University Halle
  • 1991-1997 Study of Biochemistry, Martin-Luther University Hallefinal grade “very good”

Advanced Professional Degrees

  • 2002 Ph.D. "summa cum laude"
  • 1997-2002 Ph.D. Thesis "Structure-function analysis of SU(VAR)3-9, an integral component of heterochromatic complexes." Advisor: Prof. G. Reuter, Martin-Luther-Universität, Halle

Positions held

  • since 2008 W2-Professor for Epigenetics, Adolf-Butenandt-Institute, Faculty of Medicine, Ludwig-Maximilians-Universität München
  • since 2008 Member of the ‘Center for Integrated Protein Science Munich’
  • 2003-2008 Postdoctoral fellow with Prof. T. Jenuwein, Institute of Molecular Pathology (I.M.P.), Vienna. Marie Curie Intra European Fellowship  (2004-2006)
  • 2002-2003 Postdoctoral fellow with Prof. G. Reuter, Martin-Luther-Universität,Halle


  • Reviewer for ERC (advanced grants), DFG, ETH Zurich, Dutch Cancer Foundation, several high-profile peer-reviewed journals

Selected CRC project-related publications

Srinivasachar Badarinarayan S, Shcherbakova I, Langer S, Koepke L, Preising A, Hotter D, Kirchhoff F, Sparrer KMJ, Schotta G, Sauter D. (2020) HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression. Nucleic Acids Res. 2020 Nov 4;48(19):10890-10908. doi: 10.1093/nar/gkaa832. PMID: 33021676; PMCID: PMC7641743.

Cernilogar FM, Hasenöder S, Wang Z, Scheibner K, Burtscher I, Sterr M, Smialowski P, Groh S, Evenroed IM, Gilfillan GD, Lickert H, Schotta G. (2019) Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2. Nucleic Acids Res. 2019 Sep 26;47(17):9069-9086. doi:10.1093/nar/gkz627. PMID: 31350899; PMCID: PMC6753583.

Groh S, Schotta G. (2017) Silencing of endogenous retroviruses by heterochromatin. Cell Mol Life Sci. 2017 Jun;74(11):2055-2065. doi:10.1007/s00018-017-2454-8. Epub 2017 Feb 3. PMID: 28160052.

Pasquarella A, Ebert A, Pereira de Almeida G, Hinterberger M, Kazerani M, Nuber A, Ellwart J, Klein L, Busslinger M, Schotta G. (2016) Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells. Development. 2016 May 15;143(10):1788-99. doi:10.1242/dev.130203. Epub 2016 Mar 24. PMID: 27013243.

Sadic D, Schmidt K, Groh S, Kondofersky I, Ellwart J, Fuchs C, Theis FJ, Schotta G. (2015) Atrx promotes heterochromatin formation at retrotransposons. EMBO Rep. 2015 Jul;16(7):836-50. doi: 10.15252/embr.201439937. Epub 2015 May 26. PMID: 26012739; PMCID: PMC4515123.