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Hörmanseder, Eva

Dr. Eva Hörmanseder

Junior Group Leader, IES Helmholtz Zentrum Munich


Project A30 - Propagation of active chromatin states in embryos via histone modifications


Maintaining and Reprogramming Cell Fates
Institute of Epigenetics and Stem Cells (IES)
Helmholtz Zentrum München
Marchioninistrasse 25
81377 Munich

Website: Maintaining and Reprogramming Cell Fates

Work group

Project A30

Academic Education

  • 2000 - 2006 Diploma Biology, Institute of Molecular Biotechnology (IMBA), Vienna University, Austria, Thesis supervisor: Dr. Jürgen Knoblich

Advanced Academic Qualifications

  • 2012 Doctorate in Biology, summa cum laude. Department of Cell Biology, Max Planck Institute for Biochemistry, Munich, Germany and Department of Biology, University of Konstanz, Germany Thesis supervisor: Prof. Thomas U Mayer

Professional Positions

  • since 2019 Independent Group Leader “Maintaining and Reprogramming Cell Fates”, Institute of Epigenetics and Stem Cells, Helmholtz-Zentrum Munich, Germany
  • 2013 - 2019 Postdoctoral researcher.Wellcome Trust CRUK Gurdon Institute, Cambridge University, UK. Mentor: Prof. Sir John Gurdon, FRS, Nobel laureate

Honours and Awards

  • 2019 MSCA Individual Fellowship / Horizon 2020
  • 2016 - 2019 Project grant / MR/P000479/1 / Medical Research Council / UK
  • 2015 - 2016 Sir Isaac Newton Trust Fellowship University of Cambridge /UK
  • 2013 - 2015 Long- Term Fellowship for Postdoctoral Research / EMBO
  • 2008 - 2010 DOC-fFORTE-Fellowship / Austrian Academy of Sciences
  • 2006 - 2007 Promotionsstipendium / Max-Planck-Society / Germany

Selected Publications

Oikawa M, Simeone A, Hormanseder E, Teperek M, Gaggioli V, O’Doherty A, Falk E, Sporniak M, D’Santos C, Franklin VNR, et al (2020) Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription. Nat Commun 11: 3491

Hormanseder E, Simeone A, Allen GE, Bradshaw CR, Figlmuller M, Gurdon J & Jullien J (2017) H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos. Cell Stem Cell 21: 135-143 e6

Lavagnolli T, Gupta P, Hörmanseder E, Mira-Bontenbal H, Dharmalingam G, Carroll T, Gurdon JB, Fisher AG & Merkenschlager M (2015) Initiation and maintenance of pluripotency gene expression in the absence of cohesin. Genes Dev 29: 23–38

Hormanseder E, Tischer T & Mayer TU (2013) Modulation of cell cycle control during oocyte-toembryo transitions. EMBO J 32: 2191–203 H.E. and T.T contributed equally

Tischer T, Hormanseder E & Mayer TU (2012) The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions. Science 338: 520–4 H.E. and T.T contributed equally