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Uhlenhaut, Henriette

Prof. Dr. Henriette Uhlenhaut

Molecular Endocrinology, Helmholtz Zentrum Munich


Project A21: Involvement of the COMPASS complex in the anti-inflammatory actions of the Glucocorticoid Receptor


Helmholtz Zentrum München GmbH
Institut für Diabetes und Krebs (IDC)
Ingolstätdter Landstr. 1
85764 Neuherberg

Phone: +49 (0)89 3187 2052

Website: Institute for Diabetes and Obesity: Independent Young Investigator Group Molecular Endocrinology

Work group

Project A21

Curriculum Vitae

Academic Education

  • 1996-2002 Study of Biotechnology (Diploma), Technical University of Braunschweig
  • 1999-2000 Study of Applied Biology (Master of Science), Georgia Tech, Atlanta, USA

Advanced Professional Degrees

  • 2007 Doctoral degree, EMBL & University of Heidelberg Joint International PhD Program, Advisor: Mathias Treier, EMBL Heidelberg

Positions Held

  • Since 2013 Emmy Noether Group Leader at Helmholtz Diabetes Center, Munich
  • 2010-2013 Postdoctoral fellow with Prof. Norbert Hübner, MDC Berlin
  • 2008-2010 Postdoctoral fellow with Prof. Ron Evans, The Salk Institute for Biological Studies, La Jolla, CA, USA
  • 2007-2008 Postdoctoral fellow with Prof. Mathias Treier, EMBL Heidelberg

Honours and Awards

  • 2015 Schering Foundation Friedmund Neumann Prize
  • 2014 ERC Starting Grant awarded
  • 2014-2015 Schering Foundation Young Leaders in Science program
  • 2011-2013 Fast Track Program of the Robert Bosch Foundation
  • 2010-2012 EMBO Long Term Fellowship
  • 2008-2009 Fritz Thyssen Postdoctoral Fellowship

Editorial Activities

  • since 2015 Nuclear Receptor Research

Selected CRC-related Publications

Moretti, I., Ciciliot, S., Dyar, K.A., Abraham, R., Murgia, M., Agatea, L., Akimoto, T., Bicciato, S., Forcato,M., Pierre, P., Uhlenhaut N.H., Rigby, P.W., Carvajal, J.J., Blaauw, B., Calabria, E., Schiaffino, S. (2016). MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity. Nat Commun 7,12397.

Greulich F., Hemmer M.C., Rollins D.A., Rogatsky I., Uhlenhaut N.H. (2016). There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inflammation by the glucocorticoid receptor. Steroids May 15 pii: S0039-128X(16)30035-6.

Della Torre S, Mitro N, Fontana R, Gomaraschi M, Favari E, Recordati C, Lolli F, Quagliarini F, Meda C, Ohlsson C, Crestani M, Uhlenhaut NH, Calabresi L, Maggi A. (2016). An Essential Role for Liver ERα in Coupling Hepatic Metabolism to the Reproductive Cycle. Cell Rep. 15, 360-71.

Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT. (2016). Hypothalamic leptin action is mediated by histone deacetylase 5. Nat Commun. 7, 10782.

Vettorazzi S, Bode C, Dejager L, Frappart L, Shelest E, Klaßen C, Tasdogan A, Reichardt HM, Libert C, Schneider M, Weih F, Uhlenhaut NH, David JP, Gräler M, Kleiman A and Tuckermann JP. (2015). Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. Nature  Commun. 6, 7796.